ارتباط حضور اینتگرون کلاس یک با الگوی مقاومت دارویی چندگانه در گونه های انتروباکتر جمع آوری شده از بیمارستان های آموزشی قزوین و تهران

Background: multi-drug resistant (mdr) enterobacter spp. containing class 1 integrons are considered as one of the major concerns of clinicians and infection control specialists. objective: the aim of this study was to determine the association between class 1 integrons and the multidrug resistance pattern among enterobacter spp. methods: in this analytical study, antimicrobial susceptibility pattern were determined among 137 isolates of enterobacter from qazvin and tehran hospitals during may 2011-september 2012. then all isolates were screened for class 1 integrons using pcr assay. data were analyzed using chi-square test and fisher's exact test. findings: the mdr pattern was found in 83 isolates (61%) and class 1 integrons were detected in 52 (63%) of these isolates. there was a significant association between the presence of class 1 integrons and the mdr pattern. conclusion: with regards to the results, use of proper equipment for infection control and appropriate treatment strategies are necessary.