aging and immunity in covid-19

The covid-18 pandemic severely affected people older than 65 years, especially those with age-related comorbidities, causing a disproportionate death burden in this age group. the reasons for this difference from other respiratory virus pandemics have been attributed to the aging-induced changes in the immune system, and their effects on the pathogenesis of severe acute respiratory syndrome coronavirus 2 (sars-cov-2) pneumonia. in this brief review, i summarize some of the recent findings throwing light on the relationship between aging, immunity, and the severity of covid-19.