effect of an eight-week high-intensity interval training program on serum cardiac troponin i level of streptozotocin-induced diabetic rats

Background one of the complications of diabetes, as a chronic metabolic disorder, is cardiovascular diseases. objective this study aims to investigate the effect of an eight-week high-intensity interval training (hiit) program on serum cardiac troponin i (ctni) level in streptozotocin-induced diabetic rats. methods in this experimental clinical trial, 30 rats were randomly assigned into three groups of healthy control (c), diabetic (d), and diabetic+training (d+t). the third group performed the training which included a treadmill running at an intensity of 85%-90% of maximum speed in 6-12 sessions of 2 min for 8 weeks, 5 days per week. blood glucose level and high-sensitive ctni levels were measured 48 hours after the last training session and 12 hours of fasting. one-way anova and tukey’s test were used to analyze the collected data, considering a significance level of p<0.05. findings the induction of diabetes caused a significant increase in blood glucose (p=0.01) and high-sensitive ctni (p=0.01) levels in the d group. also, a significant difference was observed in the blood glucose level of d+t group compared to the d group (p=0.001). the ctni level also slightly reduced (11%) in the d+t group compared to the d group, but it was not statistically significant (p=0.591). conclusion he hiit program can reduce the fasting blood glucose and increase the serum level of highsensitive ctni to some extent in diabetic rats; therefore, it can be an appropriate strategy for diabetics. however, there is a need for more studies in this area.