translation and psychometric evaluation of the persian version of the pediatric quality of life inventory 4.0 (pedsql 4.0) for iranian children with cancer

Introduction: measuring the health-related quality of life (hrqol) in children with cancer is very important. the pediatric quality of life inventory™ 4.0 (pedsql 4.0) is a well-established tool for measuring the hrqol of children aged 2-18 years with cancer. objective: the present study aimed to determine the psychometric properties of the persian version of the pedsql 4.0 for iranian children with cancer. materials and methods: this is a methodological study. the pedsql™ 4.0 was first translated into persian and then psychometrically evaluated. the participants included 200 children with cancer and 200 parents referred to a specialized hospital for children in rasht, iran, from october 2021 to october 2022, who were selected by a convenience sampling method. the face validity, and construct validity (by confirmatory factor analysis [cfa] were assessed. internal consistency was assessed by calculating cronbach’s α and the test re-test reliability was measured by calculating the intraclass correlation coefficient (icc). results: the mean age of children and parents was 5.9±4.2 and 37.83±5.86 years, respectively. the cfa results showed that the eight-factor model had a good fit. in the child self-report version, cronbach’s α value for the eight subscales was in the range of 0.72-0.88 and for the overall scale, it was 0.80. in the parent proxy-report version, cronbach’s α value was in the range of 0.82-0.93 and for the overall scale, it was 0.81. in the test re-test reliability, the icc value in the child self-report version for the age groups 5-7, 8-12 and 13-18 years old was 0.85, 0.78, and 1, respectively. the icc value in the parent proxy-report version for the age groups 2-4, 7-5, 8-12 and 13-18 years old was 0.97, 0.87, 0.87 and 1, respectively. conclusion: the persian version of the pedsql 4.0 has good psychometric properties for iranian children with cancer. therefore, it can be used as a valid and reliable tool to measure the hrqol of these children in iran.